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The diagnostic potential of microneedles in infectious diseases

Lookup NU author(s): Rach Dixon, Dr Wing Man LauORCiD, Professor Moein MoghimiORCiD, Dr Keng Wooi NgORCiD

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This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0).

Abstract

The coronavirus disease 2019 (COVID-19) pandemic has taught us much about our weaknesses in the management of infectious disease outbreaks. A key lesson has been the need for more effective point-of-care diagnostic tools that produce not only rapid and reliable results but also facilitate decentralised testing to avoid overwhelming central test facilities when demand peaks in an outbreak. Microneedle devices can be inserted painlessly into the skin to detect biomolecules in the epidermal and dermal layers. They have been used to identify biomarkers in b oth the interstitial fluid and capillary blood. Importantly, they are amenable to self-administration. In this article, we provide an overview of existing microneedle-based diagnostic technologies and discuss how they may be built upon to provide effective diagnostic tools for infectious diseases.

Publication metadata

Author(s): Dixon RV, Lau WM, Moghimi SM, Ng KW

Publication type: Article

Publication status: Published

Journal: Precision Nanomedicine

Year: 2020

Volume: 3

Issue: 4

Pages: 629-640

Online publication date: 06/07/2020

Acceptance date: 02/07/2020

Date deposited: 10/07/2020

ISSN (electronic): 2639-9431

Publisher: Andover House

URL: https://doi.org/10.33218/001c.13658

DOI: 10.33218/001c.13658

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