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Lookup NU author(s): Professor Andrew FisherORCiD
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© 2020 International Society for Heart and Lung Transplantation. Bronchoalveolar lavage (BAL) is a key clinical and research tool in lung transplantation (LTx). However, BAL collection and processing are not standardized across LTx centers. This International Society for Heart and Lung Transplantation–supported consensus document on BAL standardization aims to clarify definitions and propose common approaches to improve clinical and research practice standards. The following 9 areas are covered: (1) bronchoscopy procedure and BAL collection, (2) sample handling, (3) sample processing for microbiology, (4) cytology, (5) research, (6) microbiome, (7) sample inventory/tracking, (8) donor bronchoscopy, and (9) pediatric considerations. This consensus document aims to harmonize clinical and research practices for BAL collection and processing in LTx. The overarching goal is to enhance standardization and multicenter collaboration within the international LTx community and enable improvement and development of new BAL-based diagnostics.
Author(s): Martinu T, Koutsokera A, Benden C, Cantu E, Chambers D, Cypel M, Edelman J, Emtiazjoo A, Fisher AJ, Greenland JR, Hayes D, Hwang D, Keller BC, Lease ED, Perch M, Sato M, Todd JL, Verleden S, von der Thusen J, Weigt SS, Keshavjee S
Publication type: Editorial
Publication status: Published
Journal: Journal of Heart and Lung Transplantation
Year: 2020
Volume: 39
Issue: 11
Pages: 1171-1190
Print publication date: 01/11/2020
Online publication date: 14/07/2020
Acceptance date: 02/04/2018
ISSN (print): 1053-2498
ISSN (electronic): 1557-3117
Publisher: Elsevier USA
URL: https://doi.org/10.1016/j.healun.2020.07.006
DOI: 10.1016/j.healun.2020.07.006
