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Resolution of R-loops by INO80 promotes DNA replication and maintains cancer cell proliferation and viability

Lookup NU author(s): Dr Lisa PrendergastORCiD, Dr Urszula McClurg, Dr Rolando Berlinguer PalminiORCiD, Sarah Marshall, Inmaculada Hernandez Lopez, Professor Jonathan HigginsORCiD, Dr Manolis Papamichos Chronakis



This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).

Publication metadata

Author(s): Prendergast L, McClurg UL, Hristova R, Berlinguer Palmini R, Greener S, Veitch K, Hernández-López I, Pasero P, Rico D, Higgins JMG, Gospodinov A, Papamichos-Chronakis M

Publication type: Article

Publication status: Published

Journal: Nature Communications

Year: 2020

Volume: 11

Online publication date: 10/09/2020

Acceptance date: 18/08/2020

Date deposited: 23/10/2020

ISSN (electronic): 2041-1723

Publisher: Nature


DOI: 10.1038/s41467-020-18306-x


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Funder referenceFunder name
Wellcome Trust Investigator Award [106951/Z/15/Z]
Wellcome Trust Seed Award in Science (206103/Z/17/Z)