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Obesity, Sex, Race, and Early Onset Hypertension: Implications for a Refined Investigation Strategy

Lookup NU author(s): Dr Ian Logan, Dr Charlie Tomson, Professor Neil SheerinORCiD, Dr Tim Ellam

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This is the of an article that has been published in its final definitive form by American Heart Association, 2020.

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Abstract

Investigation for secondary causes is recommended in early onset hypertension. However, obesity is associated with higher blood pressure (BP), so investigation for alternative secondary causes may not be necessary in all obese patients. We sought to define a rational approach to investigation across strata of age, body mass index (BMI) sex and race, based on BP distributions in the US National Health and Nutrition Examination Surveys 2005 to 2016. The majority (71% [95% CI, 59%-79%] and 64% [95% CI, 57%-69%] by European and US definitions respectively) of early onset hypertension cases were attributable to BP distribution shifts accompanying obesity and male sex. Male versus female sex, BMI>40 versus 18.2

Publication metadata

Author(s): Thompson P, Logan I, Tomson C, Sheerin N, Ellam T

Publication type: Article

Publication status: Published

Journal: Hypertension

Year: 2020

Volume: 76

Issue: 3

Pages: 859-865

Print publication date: 01/09/2020

Online publication date: 03/08/2020

Acceptance date: 26/06/2020

Date deposited: 27/06/2020

ISSN (print): 0194-911X

ISSN (electronic): 1524-4563

Publisher: American Heart Association

URL: https://doi.org/10.1161/HYPERTENSIONAHA.120.15557

DOI: 10.1161/HYPERTENSIONAHA.120.15557

PubMed id: 32755414

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