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Epidural Versus Transabdominal Wall Catheters: A Comparative Study of Outcomes After Pancreatic Resection

Lookup NU author(s): Sanjay PandanaboyanaORCiD


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Background: This study compared epidural analgesia with local anesthetic administration via transabdominal wall catheters (TAWC), to determine the effect on perioperative outcomes in pancreatic surgery. Materials and methods: A retrospective review of patients undergoing open pancreatic surgery at Auckland City Hospital from 2015 to 2018 was undertaken. Data collected included patient demographics, type of perioperative analgesia, intravenous fluid and vasopressor use, length of high dependency unit stay, postoperative complications, and length of hospital stay. Results: Seventy-two patients underwent pancreatic surgery, of which 47 had epidural analgesia and 25 TAWC. The median age was 64 y (range 29-85). Failure of analgesia method occurred in 45% of epidural patients and 28% of TAWC patients (P = 0.209). There was no significant difference in volume of intravenous fluid given or need for vasopressors in the first 3 postoperative days, length of high dependency unit stay (median 1 d, P = 0.2836), rates of postoperative pancreatic fistula (32% versus 40%, P = 0.6046), postoperative complications (38% versus 20%, P = 0.183), or mortality (0.04% versus 0.04%, P = 1.0). Conclusions: Epidural analgesia and TAWC may have comparable perioperative outcomes in patients undergoing pancreatic surgery. Further randomized studies with a larger cohort of patients are warranted to identify the best postoperative analgesic method in patients undergoing pancreatic resection.

Publication metadata

Author(s): Perrin J, Ratnayake R, Wells C, Windsor JA, Loveday B, Maclennan N, Lindsay H, Pandanaboyana S

Publication type: Article

Publication status: Published

Journal: Journal of Surgical Research

Year: 2021

Volume: 259

Pages: 473-479

Print publication date: 01/03/2021

Online publication date: 25/10/2020

Acceptance date: 05/10/2020

ISSN (print): 0022-4804

ISSN (electronic): 1095-8673

Publisher: Elsevier


DOI: 10.1016/j.jss.2020.09.005

PubMed id: 33070995


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