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Lookup NU author(s): Dr Julie Murphy,
Emeritus Professor Doug Turnbull
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© 2020 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society and the Royal Society of Biology. In 2015, the UK became the first country to approve the use of mitochondrial donation. This novel in vitro fertilisation treatment was developed to prevent transmission of mitochondrial DNA (mtDNA) disease and ultimately give more reproductive choice to women at risk of having severely affected offspring. The policy change was a major advance that surmounted many scientific, legislative and clinical challenges. Further challenges have since been addressed and there is now an NHS clinical service available to families with pathogenic mtDNA mutations that provides reproductive advice and options, and a research study to look at the outcome at 18 months of children born after mitochondrial donation.
Author(s): Craven L, Murphy JL, Turnbull DM
Publication type: Review
Publication status: Published
Journal: Emerging Topics in Life Sciences
Print publication date: 01/09/2020
Online publication date: 23/06/2020
Acceptance date: 04/06/2020
ISSN (print): 2397-8554
ISSN (electronic): 2397-8562
Publisher: Portland Press Ltd