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Neurogenic Cough Associated with Hyperintensity in Dorsal Medulla: Case Report and Anatomical Discussion

Lookup NU author(s): Patrick Mitchell

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Abstract

© 2020Background: The nucleus tractus solitarius and paratrigeminal nucleus, which are implicated in the processing of airway-derived sensory information, are found in the dorsal medulla. The mechanism and localization of higher-order processing of urge to cough is poorly understood, and much of the existing anatomical localization is limited to animal studies. Case Description: A 44-year-old Caucasian lady underwent elective foramen magnum decompression for symptomatic Chiari I malformation; postoperatively she had resolution of Chiari symptoms but developed an intractable neurogenic cough. She has no significant medical history or premorbid respiratory issues. Postoperative magnetic resonance imaging of her head demonstrated signal change in the left dorsal medulla, corresponding with the nucleus tractus solitarius and paratrigeminal nucleus. Conclusions: We suggest that this lesion explains her isolated new cough and localizes the pathway for “urge to cough” to this region of the medulla.

Publication metadata

Author(s): Paranathala MP, Mitchell P

Publication type: Article

Publication status: Published

Journal: World Neurosurgery

Year: 2020

Volume: 144

Pages: 196-198

Print publication date: 01/12/2020

Online publication date: 22/09/2020

Acceptance date: 17/09/2020

ISSN (print): 1878-8750

ISSN (electronic): 1878-8769

Publisher: Elsevier Inc.

URL: https://doi.org/10.1016/j.wneu.2020.09.096

DOI: 10.1016/j.wneu.2020.09.096

PubMed id: 32977030

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