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Complications of synthetic mesh inserted for stress urinary incontinence

Lookup NU author(s): Professor Christopher HardingORCiD


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© 2020 The Authors BJU International © 2020 BJU International Published by John Wiley & Sons Ltd. Objective: To provide an update on the literature regarding the management of complications secondary to synthetic mesh placed to treat stress urinary incontinence (SUI). Methods: We performed a systematic review of the literature using a multi-database structured search within OVID, the Medical Literature Analysis and Retrieval System Online (MEDLINE), the Excerpta Medica dataBASE (EMBASE) and Cochrane library databases; using the keywords: urology, incontinence, mesh and surgery. Results: Several million synthetic polypropylene meshes have been inserted into women worldwide to manage SUI. Unfortunately, a significant number of women have now reported life-changing complications. We found a paucity of studies, heterogeneity of cohorts, poor long-term follow-up, and lack of evidence on the effective management of mesh-related complications. Conclusions: The contemporary evidence is low-level and often contradictory, which prevents robust recommendations regarding treatment. A prospective registry will be required to generate meaningful outcome data and help in the complex management of patients who have mesh-related complications.

Publication metadata

Author(s): Morton S, Wilczek Y, Harding C

Publication type: Review

Publication status: Published

Journal: BJU International

Year: 2021

Volume: 127

Issue: 1

Pages: 4-11

Print publication date: 01/01/2021

Online publication date: 27/09/2020

Acceptance date: 02/04/2018

ISSN (print): 1464-4096

ISSN (electronic): 1464-410X

Publisher: Blackwell Publishing Ltd


DOI: 10.1111/bju.15260

PubMed id: 32981191