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Lookup NU author(s): Christopher Harding
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© 2020 The Authors BJU International © 2020 BJU International Published by John Wiley & Sons Ltd. Objective: To provide an update on the literature regarding the management of complications secondary to synthetic mesh placed to treat stress urinary incontinence (SUI). Methods: We performed a systematic review of the literature using a multi-database structured search within OVID, the Medical Literature Analysis and Retrieval System Online (MEDLINE), the Excerpta Medica dataBASE (EMBASE) and Cochrane library databases; using the keywords: urology, incontinence, mesh and surgery. Results: Several million synthetic polypropylene meshes have been inserted into women worldwide to manage SUI. Unfortunately, a significant number of women have now reported life-changing complications. We found a paucity of studies, heterogeneity of cohorts, poor long-term follow-up, and lack of evidence on the effective management of mesh-related complications. Conclusions: The contemporary evidence is low-level and often contradictory, which prevents robust recommendations regarding treatment. A prospective registry will be required to generate meaningful outcome data and help in the complex management of patients who have mesh-related complications.
Author(s): Morton S, Wilczek Y, Harding C
Publication type: Review
Publication status: Published
Journal: BJU International
Print publication date: 01/01/2021
Online publication date: 27/09/2020
Acceptance date: 02/04/2018
ISSN (print): 1464-4096
ISSN (electronic): 1464-410X
Publisher: Blackwell Publishing Ltd
PubMed id: 32981191