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Lookup NU author(s): Dr Rhys ThomasORCiD
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© 2020 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd. Background: Sudden unexpected death in epilepsy (SUDEP) accounts for a large percentage of deaths in children with epilepsy. Contributing factors to paediatric SUDEP are incompletely understood. Aims of Study: The Epilepsy Deaths Register (EDR) is an anonymized register that compiles information on deaths related to epilepsy, across all ages and epilepsy classifications. Using the EDR, we sought to identify key risk factors for SUDEP in children to assist the development of preventive measures. Methods: All registrations between the ages of 1 and 16 years were reviewed to identify definite or probable SUDEP. These cases were analysed to identify common demographics, comorbidities, monitoring, treatments and circumstances near to the deaths. Results: We identified forty-six cases (27 males) of definite or probable SUDEP. Paediatric SUDEP is more common in a 12- to 16-year age group and in those with neuro-disability. Most paediatric SUDEP occurs during apparent sleep. There were four cases with a vagus nerve stimulator. SUDEP can occur early after the onset of seizures. Conclusions: This is the largest single cohort of SUDEP reported in children. Reports from caregivers can augment population data. Surveillance in sleep is a priority area of development.
Author(s): Craig DP, Choi YY, Hughes E, Osland K, Hanna J, Kerr MP, Thomas RH
Publication type: Article
Publication status: Published
Journal: Acta Neurologica Scandinavica
Year: 2021
Volume: 143
Issue: 5
Pages: 509-513
Print publication date: 01/05/2021
Online publication date: 19/11/2020
Acceptance date: 12/11/2020
ISSN (print): 0001-6314
ISSN (electronic): 1600-0404
Publisher: John Wiley & Sons Ltd
URL: https://doi.org/10.1111/ane.13378
DOI: 10.1111/ane.13378
PubMed id: 33210735
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