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Lookup NU author(s): Gillian Hardman, Stephen Clark, Karen Booth, Professor John Dark, Professor Andrew FisherORCiD
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND).
© 2021 The Authors. Clinical Transplantation published by John Wiley & Sons Ltd.Background: Lung transplantation is particularly susceptible to the impact of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic, and evaluation of changes to practice is required to inform future decision-making. Methods: A retrospective review of the UK Transplant Registry (UKTR) and national survey of UK lung transplant centers has been performed. Results: There was geographic variation in the prevalence of COVID-19 infection across the UK. The number of donors fell by 48% during the early pandemic period. Lung utilization fell to 10% (compared with 24% for the same period of 2019). The number of lung transplants performed fell by 77% from 53, March to May 2019, to 12. Seven (58%) of these were performed in a single-center, designated “COVID-light.” The number of patients who died on the lung transplant waiting list increased, compared to the same period of 2019 (p =.0118). Twenty-six lung transplant recipients with confirmed COVID-19 infection were reported during the study period. Conclusion: As the pandemic continues, reviewing practice and implementing the lessons learned during this period, including the use of robust donor testing strategies and the provision of “COVID-light” hospitals, are vital in ensuring the safe continuation of our lung transplant program.
Author(s): Hardman G, Sutcliffe R, Hogg R, Mumford L, Grocott L, Mead-Regan S-J, Nuttall J, Dunn S, Seeley P, Clark S, Quigley R, Al-Attar N, Booth K, Dark JH, Fisher AJ
Publication type: Article
Publication status: Published
Journal: Clinical Transplantation
Year: 2021
Volume: 35
Issue: 3
Print publication date: 01/03/2021
Online publication date: 25/12/2020
Acceptance date: 21/12/2020
Date deposited: 19/03/2021
ISSN (print): 0902-0063
ISSN (electronic): 1399-0012
Publisher: Blackwell Publishing Ltd
URL: https://doi.org/10.1111/ctr.14210
DOI: 10.1111/ctr.14210
PubMed id: 33368697
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