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Characterization of passive dosimeters in proton pencil beam scanning – A EURADOS intercomparison for mailed dosimetry audits in proton therapy centres

Lookup NU author(s): Dr Roger Harrison


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© 2021 Associazione Italiana di Fisica MedicaThe lack of mailed dosimetry audits of proton therapy centres in Europe has encouraged researchers of EURADOS Working Group 9 (WG9) to compare response of several existing passive detector systems in therapeutic pencil beam scanning. Alanine Electron Paramagnetic Resonance dosimetry systems from 3 different institutes (ISS, Italy; UH, Belgium and IFJ PAN, Poland), natLiF:Mg, Ti (MTS-N) and natLiF:Mg, Cu, P (MCP-N) thermoluminescent dosimeters (TLDs), GD-352M radiophotoluminescent glass dosimeters (RPLGDs) and Al2O3:C optically stimulated dosimeters (OSLDs) were evaluate. Dosimeter repeatability, batch reproducibility and response in therapeutic Pencil Beam Scanning were verified for implementation as mail auditing system. Alanine detectors demonstrated the lowest linear energy transfer (LET) dependence with an agreement between measured and treatment planning system (TPS) dose below 1%. The OSLDs measured on average a 6.3% lower dose compared to TPS calculation, with no significant difference between varying modulations and ranges. Both GD-352M and MCP-N measured a lower dose than the TPS and luminescent response was dependent on the LET of the therapeutic proton beam. Thermoluminescent response of MTS-N was also found to be dependent on the LET and a higher dose than TPS was measured with the most pronounced increase of 11%. As alanine detectors are characterized by the lowest energy dependence for different parameters of therapeutic pencil beam scanning they are suitable candidates for mail auditing in proton therapy. The response of luminescence detector systems have shown promises even though more careful calibration and corrections are needed for its implementation as part of a mailed dosimetry audit system.

Publication metadata

Author(s): De Saint-Hubert M, De Angelis C, Knezevic Z, Michalec B, Reniers B, Pyszka E, Stolarczyk L, Swakon J, Foltynska G, Wochnik A, Parisi A, Majer M, Harrison RM, Kopec R, Vanhavere F, Olko P

Publication type: Article

Publication status: Published

Journal: Physica Medica

Year: 2021

Volume: 82

Pages: 134-143

Online publication date: 18/02/2021

Acceptance date: 15/01/2021

ISSN (print): 1120-1797

ISSN (electronic): 1724-191X

Publisher: Associazione Italiana di Fisica Medica - Elsevier


DOI: 10.1016/j.ejmp.2021.01.073


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