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Vaccines for COVID-19: learning from ten phase II trials to inform clinical and public health vaccination programmes

Lookup NU author(s): Dr Sunil BhopalORCiD, Dr Bayanne Olabi


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© 2021 The Royal Society for Public HealthPublic health professionals and clinicians, in many countries, are immersed in the ongoing and upcoming vaccination programmes for COVID-19. Published information from vaccine trials is complex. There are important and helpful insights about the nature of the available and forthcoming vaccines, immune responses and side-effects from phase II trials. We have systematically summarised information from 10 such trials on the nature of the vaccines, exclusions from the trials, immunological effects and side-effects. Some important information within these trial reports is not available in the phase III trial articles, so a complete picture requires examination of phase II and phase III trials for each vaccine. We recommend our systematic approach for the examination of other upcoming COVID-19 vaccine phase II and III trials.

Publication metadata

Author(s): Bhopal SS, Olabi B, Bhopal R

Publication type: Article

Publication status: Published

Journal: Public Health

Year: 2021

Volume: 193

Pages: 57-60

Online publication date: 29/01/2021

Acceptance date: 21/01/2021

ISSN (print): 0033-3506

ISSN (electronic): 1476-5616

Publisher: Elsevier B.V.


DOI: 10.1016/j.puhe.2021.01.011


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