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Outcomes following PCI in CABG candidates during the COVID-19 pandemic: The prospective multicentre UK-ReVasc registry

Lookup NU author(s): Dr Mohaned Egred

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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0).


Abstract

© 2021 The Authors. Catheterization and Cardiovascular Interventions published by Wiley Periodicals LLC.Objectives: To describe outcomes following percutaneous coronary intervention (PCI) in patients who would usually have undergone coronary artery bypass grafting (CABG). Background: In the United Kingdom, cardiac surgery for coronary artery disease (CAD) was dramatically reduced during the first wave of the COVID-19 pandemic. Many patients with “surgical disease” instead underwent PCI. Methods: Between 1 March 2020 and 31 July 2020, 215 patients with recognized “surgical” CAD who underwent PCI were enrolled in the prospective UK-ReVasc Registry (ReVR). 30-day major cardiovascular event outcomes were collected. Findings in ReVR patients were directly compared to reference PCI and isolated CABG pre-COVID-19 data from British Cardiovascular Intervention Society (BCIS) and National Cardiac Audit Programme (NCAP) databases. Results: ReVR patients had higher incidence of diabetes (34.4% vs 26.4%, P =.008), multi-vessel disease with left main stem disease (51.4% vs 3.0%, P <.001) and left anterior descending artery involvement (94.8% vs 67.2%, P <.001) compared to BCIS data. SYNTAX Score in ReVR was high (mean 28.0). Increased use of transradial access (93.3% vs 88.6%, P =.03), intracoronary imaging (43.6% vs 14.4%, P <.001) and calcium modification (23.6% vs 3.5%, P <.001) was observed. No difference in in-hospital mortality was demonstrated compared to PCI and CABG data (ReVR 1.4% vs BCIS 0.7%, P =.19; vs NCAP 1.0%, P =.48). Inpatient stay was half compared to CABG (3.0 vs 6.0 days). Low-event rates in ReVR were maintained to 30-day follow-up. Conclusions: PCI undertaken using contemporary techniques produces excellent short-term results in patients who would be otherwise CABG candidates. Longer-term follow-up is essential to determine whether these outcomes are maintained over time.


Publication metadata

Author(s): Kite TA, Ladwiniec A, Owens CG, Chase A, Shaukat A, Mozid AM, O'Kane P, Routledge H, Perera D, Jain AK, Palmer N, Hoole SP, Egred M, Sinha MK, Cahill TJ, Candilio L, Anantharam B, Byrne J, Walsh SJ, McEntegart M, Kean S, Siddique L, Budgeon C, Curzen N, Berry C, Ludman P, Gershlick AH

Publication type: Article

Publication status: Published

Journal: Catheterization and Cardiovascular Interventions

Year: 2022

Volume: 99

Issue: 2

Pages: 305-313

Print publication date: 01/02/2022

Online publication date: 04/05/2021

Acceptance date: 16/03/2021

Date deposited: 11/06/2021

ISSN (print): 1522-1946

ISSN (electronic): 1522-726X

Publisher: John Wiley and Sons Inc

URL: https://doi.org/10.1002/ccd.29702

DOI: 10.1002/ccd.29702

PubMed id: 33942478


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