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Outcomes of corneal transplantation in Europe: report by the European Cornea and Cell Transplantation Registry

Lookup NU author(s): Professor Francisco Figueiredo


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Copyright © 2021 Published by Wolters Kluwer on behalf of ASCRS and ESCRS.PURPOSE: To analyze real-world graft survival and visual acuity outcomes of corneal transplantation in Europe. SETTING: Corneal clinics in 10 European Union member states, the United Kingdom, and Switzerland. DESIGN: Multinational registry study. METHODS: All corneal transplant procedures registered in the European Cornea and Cell Transplantation Registry (ECCTR) were identified. Graft survival of primary corneal transplants were analyzed using Kaplan-Meier survival curves with log-rank test and Cox regression. Corrected distance visual acuities (CDVAs) are reported at baseline and 2 years postoperatively using the Lundström distribution matrix. RESULTS: A total of 12 913 corneal transplants were identified. Overall, 32-year graft survival of corneal transplants was high (89%) but differed between indications, ranging from 98% in keratoconus and 80% for trauma. Overall, CDVA improved postoperatively, but the risk for losing vision ranged from 7% (baseline vision ≤0.1 Snellen) to 58% (baseline vision ≥1.0 Snellen). CONCLUSIONS: This report provides a comprehensive overview of graft survival and visual outcomes of corneal transplantation in Europe. In addition, it provides real-world estimates of outcomes for a variety of indications and surgical techniques to support benchmarking and demonstrates the relationship between baseline and postoperative vision.

Publication metadata

Author(s): Dunker SL, Armitage WJ, Armitage M, Brocato L, Figueiredo FC, Heemskerk MBA, Hjortdal J, Jones GLA, Konijn C, Nuijts RMMA, Lundstrom M, Dickman MM

Publication type: Article

Publication status: Published

Journal: Journal of Cataract and Refractive Surgery

Year: 2021

Volume: 47

Issue: 6

Pages: 780-785

Online publication date: 01/06/2021

Acceptance date: 02/04/2021

ISSN (print): 0886-3350

ISSN (electronic): 1873-4502

Publisher: Wolters Kluwer


DOI: 10.1097/j.jcrs.0000000000000520

PubMed id: 33278237


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