Toggle Main Menu Toggle Search

Open Access padlockePrints

Consensus for the management of pancreatic exocrine insufficiency: UK practical guidelines

Lookup NU author(s): Dr John LeedsORCiD



This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0).


© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.Pancreatic exocrine insufficiency is a finding in many conditions, predominantly affecting those with chronic pancreatitis, pancreatic cancer and acute necrotising pancreatitis. Patients with pancreatic exocrine insufficiency can experience gastrointestinal symptoms, maldigestion, malnutrition and adverse effects on quality of life and even survival. There is a need for readily accessible, pragmatic advice for healthcare professionals on the management of pancreatic exocrine insufficiency. A review of the literature was conducted by a multidisciplinary panel of experts in pancreatology, and recommendations for clinical practice were produced and the strength of the evidence graded. Consensus voting by 48 pancreatic specialists from across the UK took place at the 2019 Annual Meeting of the Pancreatic Society of Great Britain and Ireland annual scientific meeting. Recommendations for clinical practice in the diagnosis, initial management, patient education and long term follow up were developed. All recommendations achieved over 85% consensus and are included within these comprehensive guidelines.

Publication metadata

Author(s): Phillips ME, Hopper AD, Leeds JS, Roberts KJ, McGeeney L, Duggan SN, Kumar R

Publication type: Article

Publication status: Published

Journal: BMJ Open Gastroenterology

Year: 2021

Volume: 8

Issue: 1

Print publication date: 17/06/2021

Online publication date: 17/06/2021

Acceptance date: 08/05/2021

Date deposited: 28/06/2021

ISSN (electronic): 2054-4774

Publisher: BMJ Publishing Group


DOI: 10.1136/bmjgast-2021-000643


Altmetrics provided by Altmetric