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Dermatoscopic Features of Naevi During Pregnancy—A Mini Review

Lookup NU author(s): Dr Ioana Cosgarea, Dr Marco Trevisan-HerrazORCiD



This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).


© Copyright © 2021 Cosgarea, Trevisan-Herraz, Ungureanu and Zalaudek. Changes in melanocytic naevi and development of new naevi have been reported in pregnant women. The association between pregnancy and melanoma is a controversial topic. We conducted this review to identify the dermatoscopic changes that occur in naevi during pregnancy that could facilitate in distinguishing benign from suspicious lesions. Medline, Scopus, and Embase datasets were reviewed for clinical studies on dermatoscopic characteristics of melanoma and naevus in pregnancy. Six cohort studies with a total of 258 patients with 1,167 skin lesions that were examined fulfilled the conditions to be included in the review. None of the patients developed melanoma. Development of new naevi, when reported, was observed in less than half of the participants. The most frequent observed dermatoscopic change among the studies was the increase in the number of dots. Development of new vessels, hypo- and hyperpigmentations and changes in the pigment network were common described changes. The included studies were heterogeneous not allowing head-to-head comparisons between them. Robust and larger studies of dermatoscopic evaluation of naevi in pregnant women are needed to determine high-risk dermatoscopic characteristics.

Publication metadata

Author(s): Cosgarea I, Trevisan-Herraz M, Ungureanu L, Zalaudek I

Publication type: Review

Publication status: Published

Journal: Frontiers in Medicine

Year: 2021

Volume: 8

Online publication date: 09/08/2021

Acceptance date: 19/07/2021

ISSN (electronic): 2296-858X

Publisher: Frontiers Media S.A.


DOI: 10.3389/fmed.2021.727319