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Recent Advances in Conventional Methods and Electrochemical Aptasensors for Mycotoxin Detection

Lookup NU author(s): Dr Andrew Pike



This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).


The presence of mycotoxins in foodstuffs and feedstuffs is a serious concern for human health. The detection of mycotoxins is therefore necessary as a preventive action to avoid the harmful contamination of foodstuffs and animal feed. In comparison with the considerable expense of treating contaminated foodstuffs, early detection is a cost-effective way to ensure food safety. The high affinity of bio-recognition molecules to mycotoxins has led to the development of affinity columns for sample pre-treatment and the development of biosensors for the quantitative analysis of mycotoxins. Aptamers are a very attractive class of biological receptors that are currently in great demand for the development of new biosensors. In this review, the improvement in the materials and methodology, and the working principles and performance of both conventional and recently developed methods are discussed. The key features and applications of the fundamental recognition elements, such as antibodies and aptamers are addressed. Recent advances in aptasensors that are based on different electrochemical (EC) transducers are reviewed in detail, especially from the perspective of the diagnostic mechanism; in addition, a brief introduction of some commercially available mycotoxin detection kits is provided.

Publication metadata

Author(s): Ong JY, Pike AR, Tan LL

Publication type: Review

Publication status: Published

Journal: Foods

Year: 2021

Volume: 10

Pages: 1437

Print publication date: 22/06/2021

Online publication date: 22/06/2021

Acceptance date: 15/06/2021

ISSN (electronic): 2304-8158


DOI: 10.3390/foods10071437