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Lookup NU author(s): Dr Harold FellermannORCiD, Dr Bradley Brown, Professor Anil Wipat, Professor Natalio KrasnogorORCiD
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND).
We present the Infobiotics Workbench (IBW), a user-friendly, scalable, and integrated computational environment for the computer-aided design of synthetic biological systems. It supports an iterative workflow that begins with specification of the desired synthetic system, followed by simulation and verification of the system in high-performance environments and ending with the eventual compilation of the system specification into suitable genetic constructs. IBW integrates modeling, simulation, verification, and biocompilation features into a single software suite. This integration is achieved through a new domain-specific biological programming language, the Infobiotics Language (IBL), which tightly combines these different aspects of in silico synthetic biology into a full-stack integrated development environment. Unlike existing synthetic biology modeling or specification languages, IBL uniquely blends modeling …
Author(s): Konur S, Mierla L, Fellermann H, Ladroue C, Brown B, Wipat A, Twycross J, Dun BP, Kalvala S, Gheorghe M, Krasnogor N
Publication type: Article
Publication status: Published
Journal: ACS Synthetic Biology
Year: 2021
Volume: 10
Issue: 8
Pages: 1931-1945
Print publication date: 20/08/2021
Online publication date: 02/08/2021
Acceptance date: 02/04/2018
Date deposited: 21/02/2024
ISSN (electronic): 2161-5063
Publisher: American Chemical Society
URL: https://doi.org/10.1021/acssynbio.1c00143
DOI: 10.1021/acssynbio.1c00143
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