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Early postoperative functional outcomes following transoral surgery for oropharyngeal cancer: A systematic review

Lookup NU author(s): Fiona Beyer, Professor Vinidh Paleri, Dr Joanne Patterson


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© 2021 Wiley Periodicals LLC.There has been increased interest in the use of transoral surgery (TOS) for the treatment of oropharyngeal cancer (OPC). This systematic review summarizes the available evidence for validated functional outcomes following TOS for OPC, within the early postoperative period. Key databases were searched. Primary TOS resections of human subjects were included. Validated functional outcomes extracted included instrumental assessment, clinician rated, and patient reported measures. Database searches yielded 7186 titles between 1990 and December 2020. Full-text articles were obtained for 296 eligible studies, which were screened and a resulting 14 studies, comprising 665 participants were included in the review. Oropharyngeal dysfunction following TOS was observed across all three categories of outcome measures (OMs) reported and was dependent on pretreatment function, T-classification, and tumor volume. Future investigations should include optimal OMs to be used in the postoperative setting to allow for conclusive comparisons.

Publication metadata

Author(s): Stephen SE, Murphy JM, Beyer FR, Sellstrom D, Paleri V, Patterson JM

Publication type: Review

Publication status: Published

Journal: Head and Neck

Year: 2022

Volume: 44

Issue: 2

Pages: 530-547

Print publication date: 01/02/2022

Online publication date: 09/12/2021

Acceptance date: 08/11/2021

ISSN (print): 1043-3074

ISSN (electronic): 1097-0347

Publisher: John Wiley and Sons Inc


DOI: 10.1002/hed.26938