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Mechanical circulatory support in acute myocardial infarction complicated by cardiogenic shock

Lookup NU author(s): Dr Mohaned Egred, Professor Azfar Zaman, Dr Mohammad Alkhalil



This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).


© 2022 The Author(s). Published by IMR Press. Patients with acute myocardial infarction (MI) complicated by cardiogenic shock (CS) have poor prognosis. Over the last two decades, there has been some improvement in mortality rates associated with CS. Initial measures to stabilise patients should follow a shock protocol, including therapies such as volume expansion, inotropes/vasopressors, and early coronary revascularisation. The use of mechanical circulatory support (MCS) devices demonstrated better haemodynamic and metabolic profiles for patients with CS. However, these benefits have not been consistently translated into significant reductions in cardiovascular adverse events. This review aims to discuss emerging concepts related to CS including an update on its classification and pathophysiology. The focus is on recent evidence regarding the use of MCS and the timing of initiating in patients with CS.

Publication metadata

Author(s): Al-Atta A, Zaidan M, Abdalwahab A, Asswad AG, Egred M, Zaman A, Alkhalil M

Publication type: Review

Publication status: Published

Journal: Reviews in Cardiovascular Medicine

Year: 2022

Volume: 23

Issue: 2

Online publication date: 21/02/2022

Acceptance date: 27/10/2021

ISSN (print): 1530-6550

ISSN (electronic): 2153-8174

Publisher: NLM (Medline)


DOI: 10.31083/j.rcm2302071

PubMed id: 35229562