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Selumetinib in combination with dexamethasone for the treatment of relapsed/refractory RAS-pathway mutated paediatric and adult acute lymphoblastic leukaemia (SeluDex): study protocol for an international, parallel-group, dose-finding with expansion phase I/II trial

Lookup NU author(s): Dr Tobias Menne, Professor Julie Irving, Professor Ruth Plummer, Dr Geoff Shenton, Professor Gareth Veal, Dr Britta Vormoor



This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).

Publication metadata

Author(s): Menne T, Slade D, Savage J, Johnson S, Irving J, Kearns P, Plummer R, Shenton G, Veal GJ, Vormoor B, Vormoor J, Billingham L

Publication type: Article

Publication status: Published

Journal: BMJ Open

Year: 2022

Volume: 12

Print publication date: 04/03/2022

Online publication date: 04/03/2022

Acceptance date: 27/01/2022

Date deposited: 19/06/2023

ISSN (electronic): 2044-6055

Publisher: BMJ Publishing Group


DOI: 10.1136/bmjopen-2021-059872

PubMed id: 35246426


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