Browse by author
Lookup NU author(s): Professor Hamish McAllister-WilliamsORCiD
Full text for this publication is not currently held within this repository. Alternative links are provided below where available.
© 2022, SLACK Incorporated. It has been argued that reconceptualizing treatment-resistant depression as difficult-to-treat depression (DTD) is of both semantic and clinical benefit. Whereas treatment-resistant depression, by definition, most commonly focuses entirely on repeated pharmacological treatment trials, DTD takes a more holistic perspective, considering all treatment modalities — psychotherapeutic, neurostimulatory, psychosocial, self-help, and pharmacological, from a perspective of a chronic disease management model. A key element of the DTD model is frequent reviews of treatment direction, and whether additional options should be considered, including less commonly used treatments, such as implanted vagus nerve stimulation. This selective review considers the potential role of vagus nerve stimulation, both as an acute treatment and for prophylaxis, the implications of previous electroconvulsive therapy response, and the impact of the treatment on quality of life, in the context of the DTD model of care.
Author(s): McAllister-Williams RH, Costa T
Publication type: Article
Publication status: Published
Journal: Psychiatric Annals
Online publication date: 01/07/2022
Acceptance date: 02/04/2018
ISSN (print): 0048-5713
ISSN (electronic): 1938-2456
Publisher: Slack Incorporated
Altmetrics provided by Altmetric