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Lookup NU author(s): Professor Marco Carrozzo
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© 2022 Wiley Periodicals LLC.Aims: Oral lichen planus (OLP) is a chronic immune disease. In this paper, we evaluated the overall characters, clinical presentation, and outcome of gingival lesions in OLP Italian patients. Methods and Results: A retrospective cohort study was accomplished: a total of 1319 charts were investigated, of whom 922 were female (69.9%): 617 patients (46.8%) manifested white lesions and 702 red ones (53.2%). While most patients had several oral sites of involvement, the gingiva was the unique location in 103 cases. Symptoms were reported in 480 patients (36.4%): 286 patients with erosive OLP, 103 with atrophic form, and 91 with a white form. Long-lasting surveillance showed that only 40 patients (3.03%) had a total clinical signs remission. Regarding OLP medical treatment provided, patients attending less frequently a dental office underwent more often a specific therapy. Conclusions: To the best of our knowledge, this is the biggest collections of patients with gingival OLP ever described; exclusive gingival lesions are, however, rare and unlikely to undergo a malignant transformation. Moreover, gum lesions seemed to anticipate the appearance of oral lesions and a higher rate of OLP therapy was observed in patients with less frequent dental check-ups and oral hygiene instructions.
Author(s): Arduino PG, Gambino A, Macciotta A, El Haddad G, Conrotto D, Carbone M, Carrozzo M, Broccoletti R
Publication type: Article
Publication status: Published
Journal: Oral Diseases
Pages: epub ahead of print
Online publication date: 08/10/2022
Acceptance date: 02/10/2022
ISSN (print): 1354-523X
ISSN (electronic): 1601-0825
Publisher: John Wiley and Sons Inc
PubMed id: 36208128
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