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Contextual factors influencing medicines‐related interventions to support safe transitions for care home residents post hospital discharge: a systematic review and meta‐ethnographic synthesis

Lookup NU author(s): Dr Hamde Nazar, Anna Robinson-BarellaORCiD



This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).


Background Residents of care or nursing homes are at a higher risk of medication-related harm, especially during care transitions. No medicines-related intervention has been identified that supports the safe transition for these residents mov- ing into their residence following hospital discharge. A model of care integrating a number of intervention components is suggested to be most effectiveAim To investigate, via a systematic review and meta-ethnography, the factors which influence the impact of medicines related interventions.Method In December 2020, Pubmed, MEDLINE, EMBASE, PsycINFO, and CINAHL Complete were systematically searched. All studies reporting on medicines-related interventions for residents following hospital discharge were included. Quality assessment was undertaken with a validated tool. Meta-ethnography was used to investigate the factors which influ- enced how interventions did, or did not work. Findings were mapped to a validated conceptual framework for integrated care. Results From3884studies,ninemettheinclusioncriteriaandwereanalysed.Theseweregenerallyofmediumquality(n=6). The interventions were diverse: some tackled the transition process, some tackled follow-up care and some interventions involved both. The meta-ethnography, using the a priori conceptual framework, captured factors reported within the studies that influenced implementation, delivery and/or outcomes.Conclusion The review and synthesis informed the development of a conceptual model for transitionary care for this popu- lation group. Researchers and decision-makers can use this as a tool to understand their local context and inform future intervention design, implementation and evaluation in this clinical area.

Publication metadata

Author(s): Kandiah J, Nazar H, Blacklock J, Robinson A, Wright D

Publication type: Article

Publication status: Published

Journal: International Journal of Clinical Pharmacy

Year: 2022

Pages: Epub ahead of print

Online publication date: 17/11/2022

Acceptance date: 14/10/2022

Date deposited: 17/11/2022

ISSN (print): 2210-7703

ISSN (electronic): 2210-7711

Publisher: Springer Netherlands


DOI: 10.1007/s11096-022-01507-3


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