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Cutaneous manifestations of acute kidney injury

Lookup NU author(s): Dr Amaani Hussain, Dr Simon Meggitt, Professor Nick ReynoldsORCiD, Professor John SayerORCiD


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© 2022 The Author(s) 2021.Acute kidney injury (AKI) is a common medical problem with a multitude of aetiologies. Prompt diagnosis and management is key in the prevention of complications. Cutaneous signs can often give diagnostic clues of underlying systemic diseases causing AKI. This review summarizes cutaneous findings of diseases causing AKI in adults. Knowledge of such cutaneous signs could lead to earlier diagnosis of underlying kidney disease and facilitate management strategies in a timely manner. Acute interstitial nephritis, polyarteritis nodosa, Kawasaki's disease, granulomatosis with polyangiitis (previously Wegener's granulomatosis), microscopic polyangiitis, eosinophilic granulomatosis with polyangiitis (previously Churg-Strauss syndrome), Henoch-Schönlein purpura, cryoglobulinaemia, Sjögren's syndrome, systemic sclerosis, nephrogenic systemic fibrosis, dermatomyositis, systemic lupus erythematosus, amyloidosis and cholesterol embolization syndrome were highlighted as diseases causing AKI with cutaneous manifestations.

Publication metadata

Author(s): Esson GA, Hussain AB, Meggitt SJ, Reynolds NJ, Sayer JA

Publication type: Review

Publication status: Published

Journal: Clinical Kidney Journal

Year: 2022

Volume: 15

Issue: 5

Pages: 855-864

Print publication date: 01/05/2022

Online publication date: 09/12/2021

Acceptance date: 02/04/2018

ISSN (print): 2048-8505

ISSN (electronic): 2048-8513

Publisher: Oxford University Press


DOI: 10.1093/ckj/sfab255