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Lookup NU author(s): Callum Fraser, Dr Simon Whitehall
This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).
Copyright © 2022 Fraser and Whitehall.Heterochromatin is a repressive chromatin state that plays key roles in the functional organisation of eukaryotic genomes. In fungal plant pathogens, effector genes that are required for host colonization tend to be associated with heterochromatic regions of the genome that are enriched with transposable elements. It has been proposed that the heterochromatin environment silences effector genes in the absence of host and dynamic chromatin remodelling facilitates their expression during infection. Here we discuss this model in the context of the key wheat pathogen, Zymoseptoria tritici. We cover progress in understanding the deposition and recognition of heterochromatic histone post translational modifications in Z. tritici and the role that heterochromatin plays in control of genome plasticity and virulence.
Author(s): Fraser CJ, Whitehall SK
Publication type: Review
Publication status: Published
Journal: Frontiers in Genetics
Year: 2022
Volume: 13
Online publication date: 21/11/2022
Acceptance date: 04/11/2022
ISSN (electronic): 1664-8021
Publisher: Frontiers Media S.A.
URL: https://doi.org/10.3389/fgene.2022.1058741
DOI: 10.3389/fgene.2022.1058741
