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Lookup NU author(s): Dr Dennis Prangle, Sophie Harbisher, Dr Colin GillespieORCiD
This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).
© 2023 International Society for Bayesian Analysis. Most computational approaches to Bayesian experimental design require making posterior calculations repeatedly for a large number of potential designs and/or simulated datasets. This can be expensive and prohibit scaling up these methods to models with many parameters, or designs with many unknowns to select. We introduce an efficient alternative approach without posterior calculations, based on optimising the expected trace of the Fisher information, as discussed by Walker (2016). We illustrate drawbacks of this approach, including lack of invariance to reparameterisation and encouraging designs in which one parameter combination is inferred accurately but not any others. We show these can be avoided by using an adversarial approach: the experimenter must select their design while a critic attempts to select the least favourable parameterisation. We present theoretical properties of this approach and show it can be used with gradient based optimisation methods to find designs efficiently in practice.
Author(s): Prangle D, Harbisher S, Gillespie CS
Publication type: Article
Publication status: Published
Journal: Bayesian Analysis
Year: 2023
Volume: 18
Issue: 1
Pages: 133-163
Print publication date: 01/03/2023
Online publication date: 08/02/2022
Acceptance date: 02/04/2018
Date deposited: 10/01/2023
ISSN (print): 1936-0975
ISSN (electronic): 1931-6690
Publisher: International Society for Bayesian Analysis
URL: https://doi.org/10.1214/22-BA1306
DOI: 10.1214/22-BA1306
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