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This review focuses on the expanding role for biomaterials and polymer scaffolds in liver tissue engineering. Studies are subdivided into in vitro and in vivo approaches. The in vitro section of the review discusses the challenges specific to liver tissue engineering, and how the choice of scaffold and its structure influences the success of the regenerative medicine strategy. The in vivo section evaluates early attempts to stimulate liver repair with cell and growth factor therapies, their failings and how current approaches aim to solve these problems. © 2006 Future Drugs Ltd.
Author(s): Hammond JS, Beckingham IJ, Shakesheff KM
Publication type: Review
Publication status: Published
Journal: Expert Review of Medical Devices
Year: 2006
Volume: 3
Issue: 1
Pages: 21-27
Online publication date: 09/01/2014
ISSN (print): 1743-4440
ISSN (electronic): 1745-2422
URL: https://doi.org/10.1586/17434440.3.1.21
DOI: 10.1586/17434440.3.1.21
PubMed id: 16359250