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Lookup NU author(s): Yu Liu, Dr Domenico Balsamo, Professor Patrick Degenaar
This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).
© 2023 The Author(s). Published by IOP Publishing Ltd. Implantable electronic sensors and systems are utilised in an increasingly broad array of clinical applications, such as pacemakers, neuro-modulators and bioelectronic vagal nerve controllers. Advances in microelectronics, materials, and bio-interfaces allow for new clinical applications and support fundamental research. However, a longstanding issue with such devices has been the mismatch between the relative stiffness of such structures compared to tissue softness. This disparity has led to tissue rejection in the form of scar tissue around implantable probes, leading to loss of function and/or capability. This review, therefore, explores the field of implantable electronics and neuroprosthetics with a particular focus on developments in soft, flexible devices. We include advancements in materials and device topologies as well as the current understanding of their long-term efficacy in biological tissue.
Author(s): Liu Y, Balsamo D, Degenaar P
Publication type: Review
Publication status: Published
Journal: Flexible and Printed Electronics
Year: 2023
Volume: 8
Issue: 1
Online publication date: 16/03/2023
Acceptance date: 30/11/2022
ISSN (electronic): 2058-8585
Publisher: Institute of Physics
URL: https://doi.org/10.1088/2058-8585/aca779
DOI: 10.1088/2058-8585/aca779
