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Habitual physical activity levels of adults with heart failure: systematic review and meta-analysis

Lookup NU author(s): Dr Sarah Charman, Dr David Houghton, Linda Errington, Dr Guy MacGowanORCiD, Dr Leah Avery



This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0).


© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.Objective: To conduct a systematic review and meta-analysis to quantify habitual physical activity (PA) levels of patients with heart failure (HF) and assess the quality of reporting of device-assessed PA. Methods: Eight electronic databases were searched up to 17 November 2021. Data on the study and population characteristics, method of PA measurement and PA metrics were extracted. A random-effects meta-analysis (restricted maximum likelihood with Knapp-Hartung SE adjustment) was conducted. Results: Seventy-five studies were included in the review (n=7775 patients with HF). Meta-analysis was restricted to mean steps per day, encompassing 27 studies (n=1720 patients with HF). Pooled mean steps per day were 5040 (95% CI: 4272 to 5807). The 95% prediction interval for mean steps per day in a future study was 1262 to 8817. Meta-regression at the study level revealed that a 10-year increment in the mean age of patients was associated with 1121 fewer steps per day (95% CI: 258 to 1984). Conclusions: Patients with HF are a low-active population. These findings have implications for the way in which PA is targeted in patients with HF, and interventions should focus on addressing the age-related decline observed as well as increasing PA to improve HF symptoms and quality of life. PROSPERO registration number: CRD42020167786.

Publication metadata

Author(s): Jordan C, Charman SJ, Batterham AM, Flynn D, Houghton D, Errington L, MacGowan G, Avery L

Publication type: Review

Publication status: Published

Journal: Heart

Year: 2023

Volume: 109

Issue: 18

Pages: 1357-1362

Online publication date: 27/02/2023

Acceptance date: 07/02/2023

ISSN (print): 1355-6037

ISSN (electronic): 1468-201X

Publisher: BMJ Publishing Group


DOI: 10.1136/heartjnl-2022-321943

PubMed id: 36849238