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Optical Coherence Tomography Angiography Morphology After Rhegmatogenous Retinal Detachment Repair: ALIGN Post Hoc Analysis

Lookup NU author(s): Roxane Hillier

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Abstract

PURPOSE: To compare foveal avascular zone (FAZ) geometric indices using optical coherence tomography angiography (OCTA) in pneumatic retinopexy (PnR) versus pars plana vitrectomy (PPV) for rhegmatogenous retinal detachment (RRD). FAZ morphology was assessed as a possible imaging feature of retinal displacement. METHODS: This ALIGN post hoc analysis included primary fovea-off RRDs that underwent successful PnR or PPV, and performed OCTA, and fundus autofluorescence at (FAF) 3 months postoperatively at St. Michael's Hospital, Toronto, Canada. FAZ area (mm 2 ), axial ratio, circularity, and roundness were measured, and FAF images were assessed for retinal displacement. RESULTS: Seventy-two patients were included, 78% (56/72) were male mean age was 60 ± 9 years, and 60% (43/72) were phakic. Sixty-five percent (47/72) and 35% (25/72) underwent PnR and PPV, respectively. The mean baseline logarithm of the minimum angle of resolution visual acuity was 1.49 ± 0.76. FAZ circularity was lower after PPV (0.629 ± 0.120) versus PnR (0.703 ± 0.122); P = 0.016. Sixty-six patients had gradable FAF images. Retinal displacement was present in 29% (19/66), 84.2% (16/19) of which had displacement in the macula. FAZ circularity was lower in eyes with displacement in the macula (0.613 ± 0.110) versus those without displacement (0.700 ± 0.124); P = 0.015. There was a moderate negative correlation between 12-month aniseikonia and FAZ circularity(r = -0.262; P = 0.041). CONCLUSION: FAZ circularity was lower after PPV and in eyes with retinal displacement in the macula. Circularity was negatively correlated with 12-month aniseikonia scores. FAZ circularity may be another imaging feature to consider postoperatively after RRD repair.


Publication metadata

Author(s): Melo IM, Francisconi CLM, Marafon SB, Figueiredo NA, Juncal VR, Bhambra N, Ta Kim DT, Brosh K, Berger AR, Giavedoni LR, Wong DT, Altomare F, Chow DR, Hillier RJ, Muni RH

Publication type: Article

Publication status: Published

Journal: Retina: the journal of retinal and vitreous diseases

Year: 2023

Volume: 43

Issue: 5

Pages: 775-783

Print publication date: 01/05/2023

Acceptance date: 02/04/2022

ISSN (print): 0275-004X

ISSN (electronic): 1539-2864

Publisher: Lippincott Williams & Wilkins

URL: https://doi.org/10.1097/IAE.0000000000003713

DOI: 10.1097/IAE.0000000000003713

PubMed id: 36729013


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