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Antithrombotic treatment strategies in patients with established coronary atherosclerotic disease

Lookup NU author(s): Professor Vijay KunadianORCiD

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Abstract

© 2023 The Author(s). Published by Oxford University Press on behalf of the European Society of Cardiology.Multiple guidelines and consensus papers have addressed the role of antithrombotic strategies in patients with established coronary artery disease (CAD). Since evidence and terminology continue to evolve, the authors undertook a consensus initiative to guide clinicians to select the optimal antithrombotic regimen for each patient. The aim of this document is to provide an update for clinicians on best antithrombotic strategies in patients with established CAD, classifying each treatment option in relation to the number of antithrombotic drugs irrespective of whether the traditional mechanism of action is expected to mainly inhibit platelets or coagulation cascade. With the aim to reach comprehensiveness of available evidence, we systematically reviewed and performed meta-analyses by means of both direct and indirect comparisons to inform the present consensus document.


Publication metadata

Author(s): Valgimigli M, Aboyans V, Angiolillo D, Atar D, Capodanno D, Halvorsen S, James S, Juni P, Kunadian V, Landi A, Leonardi S, Mehran R, Montalescot G, Navarese EP, Niebauer J, Oliva A, Piccolo R, Price S, Storey RF, Voller H, Vranckx P, Windecker S, Fox KAA

Publication type: Article

Publication status: Published

Journal: European Heart Journal - Cardiovascular Pharmacotherapy

Year: 2023

Volume: 9

Issue: 5

Pages: 462-496

Print publication date: 01/08/2023

Online publication date: 29/04/2023

Acceptance date: 27/04/2023

ISSN (print): 2055-6837

ISSN (electronic): 2055-6845

Publisher: Oxford University Press

URL: https://doi.org/10.1093/ehjcvp/pvad032

DOI: 10.1093/ehjcvp/pvad032

PubMed id: 37120728


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