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Lookup NU author(s): Professor Gerard Stansby
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OBJECTIVES: to identify the echodensity, stenosis of carotid plaques and cerebral collateral capacity that were associated with various ipsilateral presentations (retinal, cerebrovascular, asymptomatic). DESIGN: cross-sectional study. MATERIALS: forty-four patients, with 44 plaques associated with various presentations, were studied. METHODS: the duplex images of the plaques were analysed echomorphologically in a computer by means of Grey Scale Median (GSM) [hypoechoic (low GSM), hyperechoic (high GSM)]. The percentage (%) reduction of the mean velocity in the middle cerebral artery (PRMCA) on transcranial Doppler, during clamping in carotid endarterectomy, was evaluated to distinguish the competent cerebral collateral supply (low PRMCA) from the non-competent one (high PRMCA). RESULTS: the retinal symptoms were associated with plaques of low median GSM (0), severe median stenosis (90%) and low median PRMCA (0.31) as contrasted with the cerebrovascular symptoms (17, 84%, 0.47, respectively) and asymptomatic status (32, 83%, 0.4, respectively) [(p =0.038 (GSM), p =0.67 (stenosis), p=0.15 (PRMCA)]. The retinal and the cerebrovascular symptoms were distinct in terms of PRMCA (p=0.045). CONCLUSIONS: the retinal symptoms were produced by hypoechoic and possibly embologenic plaques, whereas the cerebrovascular ones possibly by the combination of carotid embolism and a non-competent cerebral collateral circulation. Asymptomatic status was associated with the absence of any relevant mechanism.
Author(s): Stansby G; Tegos TJ; Sabetai MM; Robless P; Kalodiki E; Bassett P; Nicolaides AN
Publication type: Article
Publication status: Published
Journal: European Journal of Vascular and Endovascular Surgery
Year: 2000
Volume: 20
Issue: 5
Pages: 434-440
ISSN (print): 1078-5884
ISSN (electronic): 1532-2165
Publisher: Elsevier
URL: http://dx.doi.org/10.1053/ejvs.2000.1224
DOI: 10.1053/ejvs.2000.1224
Notes: 1078-5884 Journal Article
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