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Experiences of living with hip osteoarthritis and of receiving advice, education and ultrasound-guided intra-articular hip injection in the hip injection trial. A qualitative study

Lookup NU author(s): Dr Jenny LiddleORCiD

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This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).


Abstract

© 2023 The Authors. Musculoskeletal Care published by John Wiley & Sons Ltd.Objectives: The Hip Injection Trial (HIT) compared the effectiveness of adding a single ultrasound-guided intra-articular injection of either corticosteroid and local anaesthetic or local anaesthetic alone to advice and education among people with hip osteoarthritis (OA). This nested qualitative study explored participants' experiences of living with hip OA and of the trial treatment they received. Method: Semi-structured telephone interviews were undertaken with a purposeful sample of trial participants after a 2-month trial follow-up. Interviewers were blinded to which injection participants had received. Thematic analysis using constant comparison was undertaken prior to knowing the trial results. Results: 34 trial participants were interviewed across all arms. OA causes pain, physical limitations, difficulties at work, lowered mood, and disrupted sleep. Those who received advice and education alone felt that they had not received ‘treatment’ and described little/no benefit. Participants in both injection groups described marked improvements in pain, physical function, and other aspects of life (e.g., sleep, confidence). The perceived magnitude of benefit appeared greater among those who received the corticosteroid injection; however, the length of benefit varied in both injection groups. There was uncertainty about the longer-term benefits of injection and repeated injections. Conclusion: Hip OA is highly burdensome. Participants perceived little/no benefit from advice and education alone but reported marked improvements when combined with either injection. However, the magnitude of benefit was greater among those who received corticosteroid. The varying duration of response to injection and uncertainty regarding longer-term benefits of injection and repeated injections suggests that these areas are important for future research. Trial registration: EudraCT 2014-003412-37; ISRCTN50550256.


Publication metadata

Author(s): Holden MA, Hawarden A, Paskins Z, Roddy E, Mallen CD, Liddle J, Bourton A, Jinks C

Publication type: Article

Publication status: Published

Journal: Musculoskeletal Care

Year: 2023

Volume: 21

Issue: 4

Pages: 1601-1611

Print publication date: 11/12/2023

Online publication date: 31/10/2023

Acceptance date: 26/09/2023

Date deposited: 14/11/2023

ISSN (print): 1478-2189

ISSN (electronic): 1557-0681

Publisher: John Wiley and Sons Ltd

URL: https://doi.org/10.1002/msc.1830

DOI: 10.1002/msc.1830

Data Access Statement: The data that support the findings of this study are available from the corresponding author upon reasonable request.


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Funding

Funder referenceFunder name
Haywood Rheumatology Research and Development Foundation
National Institute for Health and Care Research
Research for Patient Benefit programme. Grant Number: PB PG 0213 30027

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