Toggle Main Menu Toggle Search

Open Access padlockePrints

Physical Activity, Inactivity and Sleep in Individuals with Hypertrophic Cardiomyopathy

Lookup NU author(s): Dr Sarah Charman, Dr Alasdair Blain, Dr Nduka OkwoseORCiD, Amy Fuller, Alaa Alyahya, Dr Kate HallsworthORCiD, Dr Christopher Eggett, Peter LukeORCiD, Dr Guy MacGowanORCiD, Professor Djordje JakovljevicORCiD


Full text for this publication is not currently held within this repository. Alternative links are provided below where available.


© 2022 Georg Thieme Verlag. All rights reserved. Physical activity presents an important cornerstone in the management and care of individuals with hypertrophic cardiomyopathy (HCM). Twenty-one individuals with HCM (age: 52±15 years old, body mass index (BMI): 30±7 kg/m 2) completed 7-day monitoring using wrist-worn triaxial accelerometers (GENEActiv, ActivInsights Ltd, UK) and were compared to age and sex-matched healthy controls (age: 51±14 years old, BMI: 25±4 kg/m 2). For individuals with HCM, clinical parameters (left atrial diameter and volume, peak oxygen consumption, NTproBNP and Minnesota Living with Heart Failure (MLHF)) were correlated with accelerometry. After adjusting for BMI, individuals with HCM spent less time in moderate-vigorous physical activity (MVPA) (86 (55-138) vs. 140 (121-149) minutes/day, p <0.05) compared to healthy controls. Individuals with HCM engaged in fewer MVPA-5 min (6 (2-15) vs. 27 (23-37) minutes/day, p <0.01) and MVPA-10 min bouts (9 (0-19) vs. 35 (17-54) minutes/day, p <0.01) versus healthy controls. For HCM only, peak oxygen consumption was correlated with MVPA (r =0.60, p <0.01) and MVPA-5 min bouts (r =0.47, p <0.05). MLHF score was correlated with slee p duration (r =0.45, p <0.05). Individuals with HCM should be encouraged to engage in moderate-intensity physical activity bouts and reduce prolonged periods of inactivity in order to potentially improve exercise tolerance and reduce disease burden.

Publication metadata

Author(s): Charman SJ, Blain AP, Okwose NC, Fuller AS, Alyahya AI, Hallsworth K, Eggett C, Luke P, Bailey K, MacGowan GA, Jakovljevic DG

Publication type: Article

Publication status: Published

Journal: International Journal of Sports Medicine

Year: 2024

Volume: 45

Issue: 02

Pages: 149-154

Print publication date: 01/02/2024

Online publication date: 27/10/2023

Acceptance date: 27/08/2023

ISSN (print): 0172-4622

ISSN (electronic): 1439-3964

Publisher: Georg Thieme Verlag


DOI: 10.1055/a-2166-3918


Altmetrics provided by Altmetric