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Prospective association of occupational and leisure-time physical activity with orthostatic blood pressure changes in older adults

Lookup NU author(s): Emerita Professor Julia Newton



This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).


© 2023, The Author(s).Orthostatic hypotension (OH) is common in older people. We examined the influence of self-reported occupational-related physical activity (PA) and leisure-time physical exercise (PE) on orthostatic response in a sample of older people over a 2 year period. Supine and orthostatic systolic blood pressure (sBP), diastolic blood pressure (dBP), and mean blood pressure (mBP) were assessed in response to Active Stand (AS) test in 205 older subjects (> 60 years old) at baseline and 2-year follow-up. OH was found in 24 subjects (11.71%) at baseline and 20 subjects (9.76%) after 2 years, with a significant degree of variability in the occurrence of OH after 2 years. Twenty-two subjects who had OH at baseline were free of it after 2 years, two subjects had persistent OH at baseline and after 2 years. After 2 years, adults with occupational PA showed no significant decrease of blood pressure in response to AS test, while lack of undertaking an occupation-related PA was significantly related with a greater decrease in sBP and mBP in response to AS testing in the 1st min. Occupation-related PA and leisure-time-related PE were related to an increase in the response of BP on AS in change between baseline and after 2 years. High between-subjects variance in OH over 2 years was noted. Occupations that involved continuous physical activity and leisure-time physical exercise in middle age were both protective for BP decline on orthostatic stress test within 2 years.

Publication metadata

Author(s): Kujawska A, Kujawski S, Dani M, Miglis MG, Hallman DM, Fudim M, Soysal P, Husejko J, Hajec W, Skierkowska-Kruszynska N, Kwiatkowska M, Newton JL, Zalewski P, Kedziora-Kornatowska K

Publication type: Article

Publication status: Published

Journal: Scientific Reports

Year: 2023

Volume: 13

Issue: 1

Online publication date: 24/11/2023

Acceptance date: 07/11/2023

Date deposited: 11/12/2023

ISSN (electronic): 2045-2322

Publisher: Nature Research


DOI: 10.1038/s41598-023-46947-7

PubMed id: 38001151


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