Introduction to bioresorbable polymers: Types and biomedical applications

Verma, D; Okhawilai, M; Goh, KL; Sharma, M; Pasbakhsh, P; Ramakrishna, S

doi:10.1016/B978-0-443-18915-9.00020-3

Introduction to bioresorbable polymers: Types and biomedical applications

Lookup NU author(s): Dr Kheng-Lim Goh ORCiD

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Abstract

Bioresorbable polymers have demonstrated notable utility in the field of biomedicine, notably in drug delivery and implantation. Materials intended for biomedical purposes must possess qualities such as nontoxicity, biocompatibility, and favorable biomechanical attributes tailored to their intended uses. Bioresorbable materials exhibit commendable biocompatibility and lack of toxicity. They find frequent application as implant materials that undergo bodily degradation via hydrolysis, obviating the need for subsequent implant/device removal surgery as the body metabolizes the degraded substances. This chapter delves into the realm of bioresorbable polymers, encompassing their categorizations and mechanisms of degradation. Various factors influencing the process of bioresorption, along with the impact of porosity on bioresorbability, are examined. The clinical applications of bioresorbable polymers and their composite forms are explained also.