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Interventions to increase vaccination in vulnerable groups: rapid overview of reviews

Lookup NU author(s): Dr Gill NormanORCiD

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Abstract

Objective: Groups which are marginalised, disadvantaged or otherwise vulnerable have lower uptake of vaccinations. This differential has been amplified in COVID-19 vaccination compared to (e.g.) influenza vaccination. This overview assessed the effectiveness of interventions to increase vaccination in underserved, minority or vulnerable groups. Methods: In November 2022 we searched four databases for systematic reviews that included RCTs evaluating any intervention to increase vaccination in underserved, minority or vulnerable groups; our primary outcome was vaccination. We used rapid review methods to screen, extract data and assess risk of bias in identified reviews. We undertook narrative synthesis using an approach modified from SWiM guidance. We categorised interventions as being high, medium or low intensity, and as targeting vaccine demand, access, or providers. Results: We included 23 systematic reviews, including studies in high and low or middle income countries, focused on children, adolescents and adults. Groups were vulnerable based on socioeconomic status, minority ethnicity, migrant/refugee status, age, location or LGBTQ identity. Pregnancy/maternity sometimes intersected with vulnerabilities. Evidence supported interventions including: home visits to communicate/educate and to vaccinate, and facilitator visits to practices (high intensity); telephone calls to communicate/educate, remind/book appointments (medium intensity); letters, postcards or text messages to communicate/educate, remind/book appointments and reminder/recall interventions for practices (low intensity). Many studies used multiple interventions or components. Conclusion: There was considerable evidence supporting the effectiveness of communication in person, by phone or in writing to increase vaccination. Both high and low intensity interventions targeting providers showed effectiveness. Limited evidence assessed additional clinics or targeted services for increasing access; only home visits had higher confidence evidence showing effectiveness. There was no evidence for interventions for some communities, such as religious minorities which may intersect with gaps in evidence for additional services. None of the evidence related to COVID-19 vaccination where inequalities of outcome are exacerbated. Prospero registration: CRD42021293355


Publication metadata

Author(s): Norman G, Kletter M, Dumville J

Publication type: Article

Publication status: Published

Journal: BMC Public Health

Year: 2024

Volume: 24

Online publication date: 03/06/2024

Acceptance date: 25/04/2024

Date deposited: 26/04/2024

ISSN (electronic): 1471-2458

Publisher: BioMed Central Ltd

URL: https://doi.org/10.1186/s12889-024-18713-5

DOI: 10.1186/s12889-024-18713-5


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Funding

Funder referenceFunder name
National Institute for Health and Care Research (NIHR) Applied Research Collaboration Greater Manchester (ARC-GM)
NIHR200174

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