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The Clinical Management of Hospitalised Patients with High Consequence Infectious Diseases in England

Lookup NU author(s): Professor Marieke Emonts-le ClercqORCiD, Dr Stephen Owens, Dr Brendan PayneORCiD, Dr Matthias Schmid, Dr Rohit Sinha

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This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).


Abstract

Infectious Diseases physicians in England have been diagnosing and managing occasional cases of viral haemorrhagic fever (VHF) since 1971, including the UK’s first case of Ebola virus disease (EVD) in 1976. Specialist isolation facilities to provide safe and effective care have been present since that time. The 2013-2016 west Africa EVD epidemics, and the emergence of Middle East respiratory syndrome (MERS) in 2012 and avian influenza A(H7N9) in 2013, led to strengthening of clinical and public health preparedness and response pathways for these types of diseases, now called High Consequence Infectious Diseases (HCIDs). The HCID Programme, led by NHS England and Public Health England between 2016 and 2018, helped to deliver these enhancements, which have been utilised on multiple occasions subsequently for new UK cases and outbreaks of mpox, avian influenza, and Lassa fever. Additionally, HCID pathways were activated for COVID-19 during the first three months of 2020, before the pandemic had been declared, while little was known about COVID-19 and HCID status had been assigned temporarily to COVID-19 as a precaution. The HCID Programme also led to the commissioning of a network of new Airborne HCID Treatment Centres in England, to supplement the existing network of Contact HCID Treatment Centres, which includes the UK’s two High Level Isolation Units. In this narrative review we describe the formation and structures of the Airborne- and Contact HCID Networks in England, their approach to safe and effective clinical management of patients with HCIDs in the UK, and the challenges they may face going forward.


Publication metadata

Author(s): Alonso A, Cohen J, Cole J, Emonts M, Karunaharan N, Meadows C, O'Hara G, Owens S, Payne B, Porter D, Ratcliffe L, Riordan A, Schmid ML, Sinha R, Tunbridge A, Whittaker L, NHS England Airborne- and Contact-HCID Networks, Beadsworth M, Dunning J

Publication type: Article

Publication status: Published

Journal: Health Security

Year: 2024

Volume: 22

Issue: Supp.1

Pages: S50-S65

Print publication date: 01/09/2024

Online publication date: 11/09/2024

Acceptance date: 18/03/2024

Date deposited: 23/05/2024

ISSN (print): 2326-5094

ISSN (electronic): 2326-5108

Publisher: Mary Ann Liebert, Inc. Publishers

URL: https://doi.org/10.1089/hs.2023.0167

DOI: 10.1089/hs.2023.0167


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