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Lookup NU author(s): Dr Fiona CampbellORCiD
This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).
© 2024 The AuthorsEvidence-based medicine (EBM) can be an unfamiliar territory for those working in tumor pathology research, and there is a great deal of uncertainty about how to undertake an EBM approach to planning and reporting histopathology-based studies. In this article, reviewed and endorsed by the Word Health Organization International Agency for Research on Cancer's International Collaboration for Cancer Classification and Research, we aim to help pathologists and researchers understand the basics of planning an evidence-based tumor pathology research study, as well as our recommendations on how to report the findings from these. We introduce some basic EBM concepts, a framework for research questions, and thoughts on study design and emphasize the concept of reporting standards. There are many study-specific reporting guidelines available, and we provide an overview of these. However, existing reporting guidelines perhaps do not always fit tumor pathology research papers, and hence, here, we collate the key reporting data set together into one generic checklist that we think will simplify the task for pathologists. The article aims to complement our recent hierarchy of evidence for tumor pathology and glossary of evidence (study) types in tumor pathology. Together, these articles should help any researcher get to grips with the basics of EBM for planning and publishing research in tumor pathology, as well as encourage an improved standard of the reports available to us all in the literature.
Author(s): Colling R, Indave I, Del Aguilla J, Cierco Jimenez R, Campbell F, Chechlinska M, Kowalewska M, Holdenrieder S, Trulson I, Worf K, Pollan M, Plans-Beriso E, Perez-Gomez B, Craciun O, Garcia-Ovejero E, Michalek IM, Maslova K, Rymkiewicz G, Didkowska J, Tan PH, Diyana Bte MD Nasir N, Myles N, Giesen C, Goldman-Levy G, Lokuhetty D, Cree IA
Publication type: Review
Publication status: Published
Journal: Modern Pathology
Year: 2024
Volume: 37
Issue: 7
Online publication date: 17/05/2024
Acceptance date: 04/05/2024
ISSN (print): 0893-3952
ISSN (electronic): 1530-0285
Publisher: Elsevier B.V.
URL: https://doi.org/10.1016/j.modpat.2024.100515
DOI: 10.1016/j.modpat.2024.100515
PubMed id: 38763419
Data Access Statement: All data generated or analyzed during this study are included in this published article.
