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Lookup NU author(s): Anna Fretwell, Dr Bano Louca, Dr Sam OrangeORCiD, Dr Fiona MalcomsonORCiD, Dr Christina DobsonORCiD, Professor Bernard Corfe
This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).
© 2024 The Author(s). Published with license by Taylor & Francis Group, LLC. Colorectal cancer incidence (CRC) is influenced by dietary factors, yet the impact of diet on CRC-specific mortality and recurrence-free survival (RFS) remains unclear. This review provides a narrative summary of existing research on dietary factors affecting CRC-specific mortality, RFS, and disease-free survival (DFS). This study searched electronic databases to identify cross-sectional/prospective research investigating dietary intake on CRC-specific mortality, RFS, or DFS. Twenty-eight studies were included in the corpus. Because of high study heterogeneity, we performed a narrative synthesis of studies. Limited, but suggestive evidence indicates beneficial effects of adhering to the American Cancer Society (ACS) guidelines and a plant rich low-carbohydrate diet on risk of CRC-specific mortality, potentially driven by fiber from cereals, vegetables, and wholegrains, but not fruit. For RFS and DFS, a Western dietary pattern, high intake of refined grains, and sugar sweetened beverages correlated with increased risk of CRC recurrence and development of disease/death. Conversely, greater adherence to the ACS dietary and alcohol guidelines, higher ω-3 polyunsaturated fatty acids, and dark fish consumption reduced risk. Our findings underscore the need for (i) standardized investigations into diet’s role in CRC survivorship, including endpoints, and (ii) comprehensive analyses to isolate specific effects within correlated lifestyle components.
Author(s): Fretwell A, Louca P, Cohoon G, Sakellaropoulou A, Henriques Caetano MDP, Koullapis A, Orange ST, Malcomson FC, Dobson C, Corfe BM
Publication type: Review
Publication status: Published
Journal: Critical Reviews in Food Science and Nutrition
Year: 2024
Pages: ePub ahead of Print
Online publication date: 11/06/2024
Acceptance date: 21/05/2024
ISSN (print): 1040-8398
ISSN (electronic): 1549-7852
Publisher: Taylor and Francis Ltd.
URL: https://doi.org/10.1080/10408398.2024.2360068
DOI: 10.1080/10408398.2024.2360068
Data Access Statement: All data used in this study is available in the corresponding manuscripts.
