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The Value of White Blood Cell Count in Predicting Serious Bacterial Infections in Children Presenting to the Emergency Department: a Multicentre Observational Study

Lookup NU author(s): Professor Marieke Emonts-le ClercqORCiD, Dr Ee Lim

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This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).

Abstract

White blood cell count (WBC) is a widely used marker for the prediction of serious bacterial infection (SBI), however previous research has shown poor performance. This study aims to assess the value of WBC in the prediction of SBI in children at the emergency department (ED) and compare its value with C-reactive protein (CRP) and absolute neutrophil count (ANC).

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Author(s): Kemps N, Vermont CL, Tan CD, von Both U, Carrol ED, Emonts M, van der Flier M, Herberg J, Kohlmaier B, Levin M, Lim E, Maconochie IK, Martinon-Torres F, Nijman RG, Pokorn M, Rivero-Calle I, Rudzāte A, Tsolia M, Zavadska D, Zenz W, Moll HA, Zachariasse JM, PERFORM consortium

Publication type: Article

Publication status: Published

Journal: Archives of Disease in Childhood

Year: 2024

Pages: epub ahead of print

Online publication date: 27/09/2024

Acceptance date: 11/09/2024

Date deposited: 12/09/2024

ISSN (print): 0003-9888

ISSN (electronic): 1468-2044

Publisher: BMJ Group

URL: https://doi.org/10.1136/archdischild-2024-327493

DOI: 10.1136/archdischild-2024-327493

ePrints DOI: 10.57711/5yfz-gc12

Data Access Statement: Data are available on reasonable request. Data of this study are available on request from the corresponding author (j.zachariasse@erasmusmc.nl), subject to local rules and regulations.

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