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Lookup NU author(s): Dr Pasquale RescignoORCiD
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© 2021, Società Italiana di Ultrasonologia in Medicina e Biologia (SIUMB).Purpose: To assess the use of the new Focal-One® HIFU platform in salvage setting to evaluate the occurrence of postoperative complications. Methods: Patients who underwent salvage HIFU (sHIFU) with Focal-One® platform were enrolled prospectively (Candiolo cancer institute—FPO IRCCS; registry number: 258/2018). Perioperative and postoperative outcomes (in terms of oncological and functional ones) were recorded during the first year of follow-up. In particular postoperative complications were classified according to Clavien–Dindo system. Results: 20 patients were enrolled. No grade 3 complications were recorded. Referring to grade 2 complications, eight patients reported urgency after 3 months of follow-up, and in 4 cases, a low urinary tract infection occurred. Evaluating the impact of sHIFU on patients’ sexual potency, micturition and quality of life, no significant deterioration was recorded during the follow-up as proven using the ANOVA analysis for repeated measurements. Only two patient had a biochemical failure after 12 months of follow-up. Conclusions: The real-time intraoperative guidance with Focal-One® platform, allows a continuous monitoring and tailoring of the treatment, with a minimization of the adverse events even in a salvage setting.
Author(s): Checcucci E, De Luca S, Piramide F, Garrou D, Mosca A, Galla A, Belli G, Russo F, Rescigno P, Poti C, Amparore D, Verri P, Volpi G, Manfredi M, Fiori C, Porpiglia F
Publication type: Article
Publication status: Published
Journal: Journal of Ultrasound
Year: 2022
Volume: 25
Issue: 2
Pages: 225-232
Print publication date: 01/06/2022
Online publication date: 24/05/2021
Acceptance date: 14/05/2021
ISSN (print): 1971-3495
ISSN (electronic): 1876-7931
Publisher: Springer Science and Business Media Deutschland GmbH
URL: https://doi.org/10.1007/s40477-021-00594-8
DOI: 10.1007/s40477-021-00594-8
PubMed id: 34031862
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