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Role of Lipoprotein(a) Reduction in Cardiovascular Disease

Lookup NU author(s): Dr Bilal Bawamia, Dr David Austin, Professor Azfar Zaman

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This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).

Abstract

© 2024 by the authors.Recent studies have shown that lipoprotein(a) (Lp(a)) is an important risk factor for a plethora of different cardiovascular diseases. It has been proven that Lp(a) levels are genetically determined and correlate with risk of cardiovascular disease, independent of lifestyle factors. As of yet, treatment options to reduce Lp(a) levels are limited, but new research into Lp(a) reduction yields promising results. This review delves into Lp(a)’s biochemistry and mechanism of effect, the association between Lp(a) and cardiovascular diseases, and possible therapies to minimise cardiovascular disease.

Publication metadata

Author(s): Schuth U, Gill K, Telyuk P, Bawamia B-R, Austin D, Zaman A

Publication type: Review

Publication status: Published

Journal: Journal of Clinical Medicine

Year: 2024

Volume: 13

Issue: 21

Online publication date: 22/10/2024

Acceptance date: 14/10/2024

ISSN (electronic): 2077-0383

Publisher: Multidisciplinary Digital Publishing Institute (MDPI)

URL: https://doi.org/10.3390/jcm13216311

DOI: 10.3390/jcm13216311

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