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Squamous cell carcinoma of the posterior pharyngeal wall: A comparative analysis of oropharyngeal origin versus hypopharyngeal origin

Lookup NU author(s): Dr Charles Kelly, Dr Laura McKenzie, Nick West

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This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).

Abstract

© 2024 Cambridge University Press. All rights reserved.Introduction Posterior pharyngeal wall (PPW) is an anatomical subsite of both oropharynx and hypopharynx. The treatment outcomes of squamous cell carcinoma (SCC) of these sites are generally published together, which makes the interpretation of data challenging. The aim of this analysis was to determine if there is any difference in treatment outcomes of these two rare disease entities. Material and Methods PPW was the primary subsite in 17 patients (1.65%) out of 1031 patients with oropharyngeal SCC, and in 23 patients (11.73%) out of 196 patients with hypopharyngeal SCC. Results Five-year overall survival was 45% for oropharyngeal origin and 53% for hypopharyngeal origin patients. There was no significant difference in survival and locoregional control between them. Conclusion SCC of the PPW is a rare entity, in our series it represents 1.65% of oropharyngeal cases and 11.73% of hypopharyngeal tumours. There was no difference in treatment outcomes between the two groups.

Publication metadata

Author(s): Kovarik PD, Cvek J, Patil R, Kelly C, Jackson M, McKenzie L, West N, Willis N, Kovarik JP, Iqbal MS

Publication type: Article

Publication status: Published

Journal: Journal of Laryngology and Otology

Year: 2024

Issue: ePub ahead of Print

Online publication date: 15/11/2024

Acceptance date: 02/04/2021

Date deposited: 03/12/2024

ISSN (print): 0022-2151

ISSN (electronic): 1748-5460

Publisher: Cambridge University Press

URL: https://doi.org/10.1017/S002221512400224X

DOI: 10.1017/S002221512400224X

PubMed id: 39545316

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