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Advances in Graphene Field Effect Transistors (FETs) for Amine Neurotransmitter Sensing

Lookup NU author(s): Dr Elmira Alimohammadzadeh, Dr John Hedley

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This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).


Abstract

© 2024 by the authors. Amine neurotransmitters (NTs) are crucial in the central nervous system, and dysregulation in their levels is implicated in a spectrum of neurological disorders. Thus, a precise and timely assessment of their concentrations is critical for early diagnosis and treatment efficacy monitoring. Graphene-based field effect transistors (GFETs) have become a ground-breaking instrument in the detection of these NTs because of their exceptional electrical characteristics and adaptability. This paper summarises the significant advancements in GFET biosensors in amine NT detection and highlights developments in the selectivity, sensitivity, and limit of detection (LOD) attained by selecting various graphene materials and functionalisation approaches.


Publication metadata

Author(s): Alimohammadzadeh E, Hedley J

Publication type: Review

Publication status: Published

Journal: Applied Sciences

Year: 2024

Volume: 14

Issue: 22

Online publication date: 05/11/2024

Acceptance date: 31/10/2024

ISSN (electronic): 2076-3417

Publisher: Multidisciplinary Digital Publishing Institute (MDPI)

URL: https://doi.org/10.3390/app142210109

DOI: 10.3390/app142210109

Data Access Statement: No new data were created or analyzed in this study. Data sharing is not applicable to this article.


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