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Residual silicone oil does appear after conventional removal and contributes to postoperative emulsification

Lookup NU author(s): Professor David SteelORCiD

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Abstract

© 2024 Lippincott Williams and Wilkins. All rights reserved. Purpose:To validate the presence of residual non-emulsified silicone oil (SO) following conventional surgical removal techniques used in vitreoretinal surgery and provide insights for optimizing surgical parameters and reducing subsequent emulsification-related complications.Methods:The two surgical steps of repeated fluid-Air exchange (FAX), including aspiration and infusion, were simulated in vitro to investigate their effectiveness in removing residual non-emulsified SO under various clinical settings. Aspiration was performed at three different positions with respect to the SO interface (i.e., within the SO phase, at the SO/BSS interface, and within the BSS phase) with a 25-gauge probe. An infusion was positioned near the SO/BSS interface with an intraoperatively standardized flow rate (5mL/min). In a further ex vivo study, the volume of residual non-emulsified SO (collected by Dichloromethane) was quantified by Flourier-Transform infrared spectroscopy (FTIR) in both repeated FAX and passive drainage (PD) groups.Results:In the in vitro model, regardless of which position a 25-gauge probe was located, residual non-emulsified SO could not be effectively removed even under high aspiration levels (p>0.05). Continuous BSS infusion led to small SO droplet formation. Residual SO in both non-emulsified and emulsified forms was observed in the ex-vivo model subjected to repeated FAX. The volume of residual non-emulsified SO was quantified, ranging from 2.75 to 24.71 L, without significant difference among experimental groups (p>0.05).Conclusions:Complete residual non-emulsified SO removal was technically challenging by conventional surgical techniques. This residual non-emulsified SO could serve as a source of ongoing SO emulsification.

Publication metadata

Author(s): Chen Y, Wang Li KK, Steel DH, Chan YK

Publication type: Article

Publication status: Published

Journal: Retina

Year: 2024

Volume: 45

Issue: 4

Pages: 630-638

Print publication date: 01/04/2025

Online publication date: 03/12/2024

Acceptance date: 02/04/2018

ISSN (print): 0275-004X

ISSN (electronic): 1539-2864

Publisher: Lippincott Williams and Wilkins

URL: https://doi.org/10.1097/IAE.0000000000004353

DOI: 10.1097/IAE.0000000000004353

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