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Women’s perspectives of molecular breast imaging: a qualitative study: Epidemiology

Lookup NU author(s): Helen Elliott, Dr Joy AllenORCiD, Dr Nerys Forester, Dr Sara Graziadio, Dr William JonesORCiD, Dr Clare LendremORCiD, Professor Mark PearceORCiD, Tim Powell, Dr Jason Scott, Dr Alison Bray

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This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).


Abstract

© The Author(s) 2024.Background: Mammography has poor sensitivity in dense breast tissue. Retrospective studies suggest that Molecular Breast Imaging (MBI), has superior diagnostic accuracy to mammography in women with very dense breast tissue. Women’s perspectives of MBI are unknown, but are crucial to understanding the feasibility of, and routes to, adoption into practice. Method: Semi-structured interviews with screened and unscreened women explored acceptability of MBI. Data were analysed thematically. Results: Four themes were generated from nineteen interviews: (1) presumed negative aspects of MBI are acceptable (2) convenience of access, (3) comfort in familiarity and (4) need for shared decisions relating to risk. Presumed negative aspects of MBI, such as radiation dose and forty-minute scan time, were acceptable provided there are benefits. Some participants were concerned about equitable access, such as parking. Participants expressed comfort in existing and familiar screening processes. Participants acknowledged that informing women of their breast density may result in increased anxiety, but it was still felt to be important to ensure women are fully informed of the risks and harms of screening. Conclusions: Women consider MBI to be an acceptable breast imaging modality. High-quality information enabling informed decision-making is essential.


Publication metadata

Author(s): Elliott H, Allen AJ, Forester ND, Graziadio S, Jones WS, Lendrem BC, Pearce MS, Powell T, Scott J, Bray A

Publication type: Article

Publication status: Published

Journal: British Journal of Cancer

Year: 2024

Issue: ePub ahead of Print

Online publication date: 18/12/2024

Acceptance date: 04/12/2024

Date deposited: 07/01/2025

ISSN (print): 0007-0920

ISSN (electronic): 1532-1827

Publisher: Springer Nature

URL: https://doi.org/10.1038/s41416-024-02930-1

DOI: 10.1038/s41416-024-02930-1

Data Access Statement: The datasets generated and analysed during the current study are not publicly available due to legal frameworks protecting participant data, but anonymised quotes are available from the corresponding author on reasonable request.


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Funding

Funder referenceFunder name
Innovate UK
NIHR Newcastle In Vitro Diagnostics Co-operative (ref MIC-2016-014)

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