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Lookup NU author(s): Dr Katherine DuncanORCiD
This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).
© 2024 The Authors. Pseudonocardia species comprise a genus of filamentous, sporulating bacteria belonging to the phylum Actinomycetota, formerly Actinobacteria. They are found in marine and freshwater sediments and soils and associated with marine animals, insects, and plants. To date, they have mostly been studied because of their mutually beneficial symbiosis with fungus-growing ants in the tribe Attini. They have also attracted interest due to their biosynthetic capabilities, including the production of variably glycosylated polyenes and other novel antifungal compounds, and for their capacity to grow on a variety of hydrocarbons. The majority of clinically used antibiotics are derived from the specialised metabolites of filamentous actinomycete bacteria and most of these come from the genus Streptomyces. However, in the quest for novel chemistry there is increasing interest in studying other filamentous actinomycete genera, including Pseudonocardia. Here we outline the biological properties, genome size and structure and key features of the genus Pseudonocardia, namely their specialised metabolites and ecological roles.
Author(s): Whatmough B, Holmes NA, Wilkinson B, Hutchings MI, Parra J, Duncan KR
Publication type: Article
Publication status: Published
Journal: Microbiology
Year: 2024
Volume: 170
Issue: 9
Online publication date: 19/09/2024
Acceptance date: 27/08/2024
Date deposited: 22/01/2025
ISSN (print): 1350-0872
ISSN (electronic): 1465-2080
Publisher: Microbiology Society
URL: https://doi.org/10.1099/mic.0.001501
DOI: 10.1099/mic.0.001501
PubMed id: 39297772
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