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A diagnostic host-specific transcriptome response for Mycoplasma pneumoniae pneumonia to guide pediatric patient treatment

Lookup NU author(s): Professor Marieke Emonts-le ClercqORCiD

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Author(s): Viz-Lasheras S, Gómez-Carballa A, Bello X, Rivero-Calle I, Dacosta AI, Kaforou M, Habgood-Coote D, Emonts M, Herberg JA, Wright VJ, Carrol ED, Paulus SC, Zenz W, Kohlfürst DS, Schweintzger N, Van der Flier M, de Groot R, Schlapbach LJ, Agyeman P, Pollard AJ, Fink C, Kuijpers TT, Anderson S, EUCLIDS Consortium, PERFORM Consortium, DIAMONDS Consortium

Publication type: Article

Publication status: Published

Journal: Nature Communications

Year: 2025

Volume: 16

Online publication date: 15/01/2025

Acceptance date: 05/01/2025

Date deposited: 28/01/2025

ISSN (electronic): 2041-1723

Publisher: Nature Publishing Group

URL: https://doi.org/10.1038/s41467-025-55932-9

DOI: 10.1038/s41467-025-55932-9

Data Access Statement: New RNAseq data generated in this study and used for validation are available in ArrayExpress repository (https://www.ebi.ac.uk/biostudies/arrayexpress) under accession number E-MTAB-14588. RNASeq data previously analyzed in other studies are available in ArrayExpress under accession numbers E-MTAB-12793 and E-MTAB-14564 and in Gene Expression Omnibus NCBI (GEO; http://www.ncbi.nlm.nih.gov/geo/) under accession number GSE261482. Details are provided in Supplementary Data 4. Code availability Original R code has been deposited at github (https://github.com/Sandraviz/Mycoplasma-pneumoniae_-Transcriptomic-Signatures.git), https://doi.org/10.5281/zenodo.14258748 52.

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